APS uses several closely related concepts because different explanatory questions disclose different aspects of the same living organisation. These concepts are not competing definitions, independent causes, components, or levels of biological reality.

Question APS Concept
What is life? Viability-oriented, constraint-closed organisation
What distinguishes organisationally consequential conditions? Viability
How are the conditions of continued organisation mutually maintained? Constraint closure
What do living systems do? Agency
How is organisational continuity maintained through change? Process
Across what spatial and temporal extents is persistence organised? Scale
What persists through biological change? Organised persistence

Agency, Process, and Scale have a particular relationship within this architecture. They are complementary analytic projections of one biologically real organisation: Agency concerns what living systems do; Process concerns how continuity is maintained despite change; and Scale concerns where persistence is organised across spatial and temporal extents. They are not separate systems, stages, levels, or causal domains.

Viability and constraint closure characterise the organisation being examined. Viability distinguishes conditions according to their consequences for continued functioning, while constraint closure identifies organisational dependencies through which the system contributes to maintaining the conditions of its own continuation. Organised persistence characterises the resulting continuity: persistence achieved through continuing organisation rather than material sameness or structural invariance.

APS therefore uses different concepts not to divide living systems into separate realities, but to distinguish explanatory questions about the same viability-oriented, constraint-closed organisation.