Diagnostics and Empirical Tractability

Perturbation, malfunction, diagnosis, biosignatures, life detection, evidence, failure, and operational analysis of living systems.

This cluster examines how APS concepts become empirically tractable. It concerns how living organisation is identified, tested, diagnosed, and distinguished from breakdown, malfunction, or non-living organisation.

Result

Articles

Syntheses

  • Diagnosing Agency — Biosignatures, Perturbations, and the Empirical Tractability of Life

    Diagnosis Synthesis

    If agency is the defining activity of life, it must be empirically tractable. In the Agency–Process–Scale (APS) framework, agency can be investigated through two complementary forms of evidence: organisational signatures and perturbation responses. Organisational signatures reveal the stable patterns produced by viability-oriented activity, while perturbation responses reveal the regulatory dynamics through which viability is maintained. Together they provide a unified framework for diagnosing living systems, evaluating marginal cases, and extending life detection beyond familiar biological contexts.

    Revised: 2026-06-15

Glossary Entries

  • Diagnosis

    Diagnosis Glossary

    Diagnosis is the evaluation of a system’s viability-oriented organisation through its response to perturbation.

    Revised: 2026-06-15

  • Malfunction

    Diagnosis Glossary

    In APS, malfunction refers to continuity impairment within organised persistence. Malfunction is not merely the failure of an isolated component, but the disruption of organisational relations required for sustaining viable continuity across interacting biological processes and scales.

    Revised: 2026-06-15

  • Perturbation

    Diagnosis Glossary

    Perturbation is the probing of a system’s viability-oriented organisation through targeted disturbance.

    Revised: 2026-06-15

  • Resilience

    Diagnosis Glossary

    In APS, resilience refers to the continuity-preserving capacity of living systems under perturbation. Resilience is expressed through regulation, compensation, recovery, adaptive flexibility, and organisational reorganisation that sustain viable persistence across changing conditions.

    Revised: 2026-06-15

  • Virus

    Diagnosis Glossary

    A virus is a biologically active replicator that depends upon host organisation for persistence.

    Revised: 2026-06-23