Enabling Dependency is a form of organisational dependency in which one form of organisation establishes conditions that make another form of organisation possible without constituting it.

The later phenomenon depends upon the earlier organisation while remaining organisationally distinct from it. The earlier organisation provides conditions of possibility, but the later phenomenon possesses its own explanatory role, organisational properties, and forms of activity.

Within APS, the relationship between Biological Evaluation and Significance illustrates enabling dependency. Significance depends upon evaluative activity because evaluation establishes conditions under which mattering becomes possible. However, significance is not identical with evaluation and retains its own explanatory status.

Many APS pathways involving significance, integration, cognition, mind, selfhood, reflective agency, and meaning are understood as enabling dependencies.