Scientific frameworks do not become stronger by eliminating every unanswered question. They become stronger by identifying which questions remain open and by providing productive ways to investigate them.
All major scientific theories contain unresolved problems, areas of uncertainty, and opportunities for refinement. Such challenges are not signs of failure. They are often signs that a framework has progressed beyond initial formulation and entered a phase of critical evaluation and development.
APS is no exception. Questions concerning agency, operationalisation, empirical application, and relationships to other theoretical frameworks are important areas for ongoing research. Addressing these questions is part of the framework’s continued maturation.
The goal of APS is not to provide a final or complete account of life. Its aim is to offer an explanatory framework capable of clarifying biological organisation, generating new questions, and supporting further scientific investigation.
A theory should therefore be judged not only by the problems it has solved, but also by the quality of the problems it helps reveal.